Inflammation is the body's protective response to irritation, injury, or infection. It's characterized by redness, heat, pain, swelling, and sometimes loss of function. When tissues are damaged, the body triggers an inflammatory cascade to heal and repair. Acute inflammation happens after an injury or infection. Blood vessels dilate, and leukocytes migrate to the site. This helps destroy invaders and remove debris to set the stage for healing. Signs appear within minutes or hours, and usually resolve after a few days. Chronic inflammation lingers for months or years. It occurs due to:
- Autoimmune disorders
- Persistent infections
- Exposure to irritants
- Faulty inflammatory processes
- Heart disease
- Diabetes
- Arthritis
- Cancer
- Resolution: The ideal outcome. Inflammatory mediators clear debris and repair tissue. Signs dissipate as balance is restored.
- Progression to chronic inflammation: Damaging inflammation persists, promoting disease progression.